Dylan Kotliar

Dylan Kotliar is in the MD/PhD program at Harvard Medical School in the Health Sciences and Technology track and the Harvard Systems Biology PhD program. Coming from a background in cancer genomics, Dylan is a graduate student in the lab employing his statistics background to assess evidence for evolutionary selection in the genomes of humans and pathogens. He is a co-leader on genome-wide association studies of susceptibility to Ebola Virus Disease and Lassa Fever. In addition, he has developed a novel computational framework for measuring and quantifying the strength of purifying selection in cancer genomes.

SELECTED PUBLICATIONS

Direct Identification of Hundreds of Expression-Modulating Variants using a Multiplexed Reporter Assay.

Cell. 2016.
Tewhey R, Kotliar D, Park DS, Liu B, Winnicki S, Reilly SK, Andersen KG, Mikkelsen TS, Lander ES, Schaffner SF, Sabeti PC.

Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia.

Cancer Cell. 2016.
Wang L, Brooks AN, Fan J, Wan Y, Gambe R, Li S, Hergert S, Yin S, Freeman SS, Levin JZ, Fan L, Seiler M, Buonamici S, Smith PG, Chau KF, Cibulskis CL, Zhang W, Rassenti LZ, Ghia EM, Kipps TJ, Fernandes S, Bloch DB, Kotliar D, Landau DA, Shukla SA, Aster JC, Reed R, DeLuca DS, Brown JR, Neuberg D, Getz G, Livak KJ, Meyerson MM, Kharchenko PV, Wu CJ.

Medical education in the United States: do residents feel prepared?

Perspectives in Medical Education. 2015. In press
Chen (Amy) Chen, Dylan Kotliar, Brian C. Drolet*

Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia.

Cancer Cell. 2014.
Dan A Landau; Kendell Clement; Michael J Ziller; Patrick Boyle; Jean Fan; Hongcang Gu; Kristen Stevenson; Carrie Sougnez; Lili Wang; Shuqiang Li;Dylan Kotliar; Wandi Zhang; Mahmoud Ghandi; Levi Garraway; Stacey M Fernandes; Kenneth J Livak; Stacey Gabriel; Andreas Gnirke; Eric S Lander; Jennifer R Brown; Donna Neuberg; Peter V Kharchenko; Nir Hacohen; Gad Getz; Alexander Meissner; Catherine J Wu

Integration of genomic data enables selective discovery of breast cancer drivers.

Cell. 2014.
Sanchez-Garcia F, Villagrasa P, Matsui J, Kotliar D, Castro V, Akavia UD, Chen BJ, Saucedo-Cuevas L, Rodriguez Barrueco R, Llobet-Navas D, Silva JM, Pe'er D.

An Integrated Approach to Uncover Drivers of Cancer.

Cell. 2010.
Uri David Akavia, Oren Litvin, Jessica Kim, Felix Sanchez Garcia, Dylan Kotliar, Helen C. Causton, Panisa Pochanard, Eyal Moses, Levi A. Garraway, Dana Pe'er

DYLAN KOTLIAR

SELECTED PUBLICATIONS

Cell. 2016. Tewhey R, Kotliar D, Park DS, Liu B, Winnicki S, Reilly SK, Andersen KG, Mikkelsen TS, Lander ES, Schaffner SF, Sabeti PC.

Perspectives in Medical Education. 2015. In press Chen (Amy) Chen*, Dylan Kotliar*, Brian C. Drolet*

Cell. 2014. Sanchez-Garcia F, Villagrasa P, Matsui J, Kotliar D, Castro V, Akavia UD, Chen BJ, Saucedo-Cuevas L, Rodriguez Barrueco R, Llobet-Navas D, Silva JM, Pe'er D.

Cell. 2010. Uri David Akavia, Oren Litvin, Jessica Kim, Felix Sanchez Garcia, Dylan Kotliar, Helen C. Causton, Panisa Pochanard, Eyal Moses, Levi A. Garraway, Dana Pe'er

Cell. 2016.
Tewhey R, Kotliar D, Park DS, Liu B, Winnicki S, Reilly SK, Andersen KG, Mikkelsen TS, Lander ES, Schaffner SF, Sabeti PC.

Perspectives in Medical Education. 2015. In press
Chen (Amy) Chen, Dylan Kotliar, Brian C. Drolet*

Cell. 2014.
Sanchez-Garcia F, Villagrasa P, Matsui J, Kotliar D, Castro V, Akavia UD, Chen BJ, Saucedo-Cuevas L, Rodriguez Barrueco R, Llobet-Navas D, Silva JM, Pe'er D.

Cell. 2010.
Uri David Akavia, Oren Litvin, Jessica Kim, Felix Sanchez Garcia, Dylan Kotliar, Helen C. Causton, Panisa Pochanard, Eyal Moses, Levi A. Garraway, Dana Pe'er