Rachel Sealfon

Rachel Sealfon is a graduate student in the Department of Electrical Engineering and Computer Science at MIT. She is from Brooklyn, New York and attended Hunter College High School. She graduated summa cum laude from Princeton University and received her master’s degree in computer science from MIT. She has won the Computing Research Association Outstanding Female Undergraduate Award, NSF and NDSEG fellowships, and was a Hertz Fellowship finalist. She develops and applies methods to understand microbial genomics and evolution, and is especially interested in exploring how computational approaches can help combat under-studied infectious diseases. She has studied pathogens including P. falciparum, Vibrio cholerae, Lassa virus, and Ebola virus. Outside lab, she especially enjoys cooking, reading, and hiking.


Gire et al., Genomic surveillance elucidates Ebola virus origin and
transmission during the 2014 outbreak.

Sealfon et al., High depth, whole-genome sequencing of cholera
isolates from Haiti and the Dominican Republic, 2012,

Predicting enhancer regions and transcription factor binding sites in
D. melanogaster. Master’s thesis. Sealfon, Rachel. (Massachusetts
Institute of Technology, 2010)

Negre et al., A cis-regulatory map of the Drosophila genome.

Roy et al., Identification of functional elements and regulatory
circuits by Drosophila modENCODE.

Sealfon, Rachel (2008): Integration of Heterogeneous Data Sources to
Generate a Genome-Wide Functional Interaction Network in the Malaria
Parasite P. falciparum. Senior thesis, Princeton University.

GOLEM: an interactive graph-based gene-ontology navigation and
analysis tool, BMC Bioinformatics, 2006.