Danny Park is the Group Leader for Viral Computational Genomics at the Broad Institute of MIT and Harvard. Under the direction of Pardis Sabeti, Danny leads genomic analyses and the development of computational methods for viral projects in the lab, including work on Ebola, Lassa, and unidentified viral fevers, and directs the implementation of computational pipelines for use both at the Broad and at collaborating research institutions in Africa.
Danny originally worked with the Sabeti Lab as a software engineer at the Broad, then as a Harvard graduate student (with support from the National Science Foundation), where he earned his PhD in Organismic and Evolutionary Biology. During this time, he developed and utilized computational tools to identify adaptations in the P. falciparum malaria parasite that allow it to evade modern drugs and global eradication efforts. Prior to the Broad, he spent four years at a microarray core facility at MGH, working as a bioinformatic consultant on the design and analysis of expression experiments. His bachelor's and master's degrees are in computer science from MIT, where he developed software tools for in silico protein design in the Keating Lab. He lives in Cambridge with his wife and son.
Ebola Virus Epidemiology, Transmission, and Evolution during Seven Months in Sierra Leone
Cell. 18 June 2015.
Park DJ, Dudas G, Wohl S, Goba A, Whitmer SL, Andersen KG, Sealfon RS, Ladner JT, Kugelman JR, Matranga CB, Winnicki SM, Qu J, Gire SK, Gladden-Young A, Jalloh S, Nosamiefan D, Yozwiak NL, Moses LM, Jiang PP, Lin AE, Schaffner SF, Bird B, Towner J, Mamoh M, Gbakie M, Kanneh L, Kargbo D, Massally JL, Kamara FK, Konuwa E, Sellu J, Jalloh AA, Mustapha I, Foday M, Yillah M, Erickson BR, Sealy T, Blau D, Paddock C, Brault A, Amman B, Basile J, Bearden S, Belser J, Bergeron E, Campbell S, Chakrabarti A, Dodd K, Flint M, Gibbons A, Goodman C, Klena J, McMullan L, Morgan L, Russell B, Salzer J, Sanchez A, Wang D, Jungreis I, Tomkins-Tinch C, Kislyuk A, Lin MF, Chapman S, MacInnis B, Matthews A, Bochicchio J, Hensley LE, Kuhn JH, Nusbaum C, Schieffelin JS, Birren BW, Forget M, Nichol ST, Palacios GF, Ndiaye D, Happi C, Gevao SM, Vandi MA, Kargbo B, Holmes EC, Bedford T, Gnirke A, Ströher U, Rambaut A, Garry RF, Sabeti PC
Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak
Gire SK, Goba A, Andersen KG, Sealfon RS, Park DJ, Kanneh L, Jalloh S, Momoh M, Fullah M, Dudas G, Wohl S, Moses LM, Yozwiak NL, Winnicki S, Matranga CB, Malboeuf CM, Qu J, Gladden AD, Schaffner SF, Yang X, Jiang PP, Nekoui M, Colubri A, Coomber MR, Fonnie M, Moigboi A, Gbakie M, Kamara FK, Tucker V, Konuwa E, Saffa S, Sellu J, Jalloh AA, Kovoma A, Koninga J, Mustapha I, Kargbo K, Foday M, Yillah M, Kanneh F, Robert W, Massally JL, Chapman SB, Bochicchio J, Murphy C, Nusbaum C, Young S, Birren BW, Grant DS, Scheiffelin JS, Lander ES, Happi C, Gevao SM, Gnirke A, Rambaut A, Garry RF, Khan SH, Sabeti PC.
Sequence-based association and selection scans identify drug resistance loci in the Plasmodium falciparum malaria parasite
Proc Natl Acad Sci U S A. 2012.
Park DJ, Lukens AK, Neafsey DE, Schaffner SF, Chang HH, Valim C, Ribacke U, Van Tyne D, Galinsky K, Galligan M, Becker JS, Ndiaye D, Mboup S, Wiegand RC, Hartl DL, Sabeti PC, Wirth DF, Volkman SK.
Harnessing genomics and genome biology to understand malaria biology
Nat Rev Genet. 2012.
Volkman SK1, Neafsey DE, Schaffner SF, Park DJ, Wirth DF.
Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum
PLoS Genet. 2011.
Van Tyne D1, Park DJ, Schaffner SF, Neafsey DE, Angelino E, Cortese JF, Barnes KG, Rosen DM, Lukens AK, Daniels RF, Milner DA Jr, Johnson CA, Shlyakhter I, Grossman SR, Becker JS, Yamins D, Karlsson EK, Ndiaye D, Sarr O, Mboup S, Happi C, Furlotte NA, Eskin E, Kang HM, Hartl DL, Birren BW, Wiegand RC, Lander ES, Wirth DF, Volkman SK, Sabeti PC.