Our lab develops and uses computational tools to scan the genome for loci of positive selection, as well as analyzing datasets in genomics and global health.
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We investigate the adaptive alleles that our computational methods identify in order to determine their biological function and evolutionary history.
We apply our computational methods to the genomes of pathogens and their host populations to find out how these diseases evolve.
Dr. Pardis Sabeti is an Assistant Professor at the Center for Systems Biology at Harvard University, Department of Organismic and Evolutionary Biology, and a Senior Associate Member of the Broad Institute of Harvard and MIT. Dr. Sabeti is a computational geneticist with expertise studying genetic diversity, developing algorithms to detect genetic signatures of natural selection, and carrying out genetic association studies.